October Update

Bought a standard poodle puppy.  Bringing him home October 5, so October will be full of housebreaking, and FUN.

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ASK THE SCIENCE WRITER > Spliced RNA and link to cancer

You mention the spliced RNA messengers in your article. Are cancer cells formed when these edited segments go awry? Or is this mechanism of splicing and editing altered after the formation of cancer cells? In otherwords, does one cause the other?

July 24, 2007 | Unregistered CommenterMark

Hi, Mark, Actually either one might happen. But most likely is the first. Incorrect splicing could potentiate oncogenes, the ones that can cause cancer, or could interfere with tumor suppressing genes, the ones that catch cancerous changes before cancer starts. Also, cancer cells become so badly disorganized as far as chromosomes are concerned, there could be splicing problems that result. You might like this website: :http://cancerres.aacrjournals.org/cgi/content/abstract/64/21/7647

July 27, 2007 | Unregistered CommenterJulie Simon Lakehomer